Familial Hypertriglyceridemia in Children: Dietary Management

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Dietary management of familial hyperlipidaemias

The rising incidence of coronary heart disease (CHD) in affluent populations has focused attention onto predisposing risk factors, among them high blood levels of cholesterol and triglyceride. In some inherited disorders characterized by hyperlipidaemia the risk of developing CHD is extremely high, and attempts at preventing CHD should in the main concentrate on these individuals in view of the...

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Dietary management of familial hyperlipidaemias.

The rising incidence of coronary heart disease (CHD) in affluent populations has focused attention onto predisposing risk factors, among them high blood levels of cholesterol and triglyceride. In some inherited disorders characterized by hyperlipidaemia the risk of developing CHD is extremely high, and attempts at preventing CHD should in the main concentrate on these individuals in view of the...

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Plasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia.

Plasma lipoprotein concentration, composition, and size were evaluated in two common familial forms of hypertriglyceridemia and compared with those in normal subjects. The very low density lipoproteins (VLDL) were triglyceride-enriched in familial hypertriglyceridemia (triglyceride/apoprotein B ratio: 25.7 +/- 8.9) as compared to normal (9.6 +/- 12.2, P < 0.001) or familial combined hyperlipide...

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Familial hypertriglyceridemia-induced acute necrotizing pancreatitis: A case report

Acutepancreatitis can infrequently be a life-threatening complication of hypertriglyceridemia. Rarely, hypertriglyceridemia can originate from an inborn genetic error in lipoproteins metabolism. This condition can be manifested by very high serum triglyceride levels (>1000 mg/dl) and a more severe and lethal form of pancreatitis. Here, we present a case of acute pancreatic which was found out t...

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Abnormal lipoprotein lipase in familial exogenous hypertriglyceridemia.

A 5-yr old male proband and his sister have had hypertriglyceridemia and hepatosplenomegaly since birth. When studied on a metabolic ward, they demonstrated rapid decreases in serum triglycerides on 3 g fat/day diets. Oral glucose tolerance tests were normal. Postheparin lipolytic activity (PHLA) against chylomicrons was virtually absent in both children whereas the mother and a normolipemic si...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1977

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-197709000-00003